Category: News

Give a Toss for Huntington’s Disease

This video is an awareness campaign highlighting the impact that the toss of a “genetic coin” has had on three recent generations of one family. It is thought that there are up to 12,000 other HD families in the UK.  

UCC Researchers focus on gene silencing approaches for HD Hope

Prof. John F. Cryan and Prof. Caitriona O’Driscoll, two researchers in University College Cork ,Ireland with very different backgrounds & expertise came together to combine their research efforts to develop therapies for Huntington’s Disease. In an article published recently Professor Cryan discusses the progress of this collaborative work: Read the article here

Through the eyes of a friend: changes in mood and behavior in early HD

Companions of HD gene carriers are more likely to notice psychological changes in presymptomatic HD. The family and friends of individuals with HD often tell doctors that they began to notice changes in behavior long before a diagnosis was made. To better understand these early signs, researchers analyzed a psychological questionnaire filled out yearly for…
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huntingtons disease trial

A multiple sclerosis drug that works for Huntington’s disease: the real deal or too good to be true?

Thinking problems in Huntington’s disease take a huge toll from early in the disease. Now, new work suggests that a drug already approved by the FDA to treat another brain disease – multiple sclerosis – may stave off these problems in HD mice. Could these results be real, or are they too good to be…
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Mapping the anatomy of HD: a whole-brain history

Though many scientists have focused on damage to a part of the brain called the striatum as a source of HD symptoms, this is a narrow picture of what changes in the brain during HD. A new book provides a summary of many research techniques over a hundred years that have led to a more…
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Huntington’s Patients Often Also Suffer from Psychiatric Disorders

According to the findings of a recent study published in The American Journal of Psychiatry psychiatric manifestations develop more often than previously thought during Huntington’s disease prodrome. Moreover, it appears that symptoms increase with disease severity. Early features of Huntington’s disease can include mood swings, personality changes, fidgety movements, irritability and altered behavior, although these are…
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Story of search for Huntington’s cure wins science writing prize

Australian author and journalist Christine Kenneally has won The Bragg UNSW Press Prize for Science Writing for her article The Past May Not Make You Feel Better, about the search for a cure for Huntington’s disease. President of the Business Council of Australia, Catherine Livingstone, announced the winner of the $7000 prize at a ceremony on…
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Liftoff: First humans treated with gene silencing drugs for HD!

Originally published on HD Buzz on October 19, 2015 (By Dr Jeff Carroll on October 22, 2015, Edited by Dr Tamara Maiuri ) Today brings news that the first Huntington’s Disease patients have been successfully dosed with gene silencing drugs targeting the HD gene. These brave volunteers are the first HD patients to ever be…
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