Category: Research

Thiol-disulfide Oxidoreductases TRX1 and TMX3 Decrease Neuronal Atrophy…

Thiol-disulfide Oxidoreductases TRX1 and TMX3 Decrease Neuronal Atrophy in a Lentiviral Mouse Model of Huntington’s Disease Below is an abstract from a scientific report by Jonathan Fox, Zhen Lu and Lorraine Barrows. The full report is available here at PLOS Currents.   ABSTRACT Huntington’s disease (HD) is caused by a trinucleotide CAG repeat in the…
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Huntington’s Research Sheds Light on Proteins’ Shift to Fibrous Solids

On Huntingtonsdiseasenews.com Ana Pampolna reports that recent research has shed light on how some proteins are converted into liquid droplets before becoming toxic fibrous solids that are involved in neurodegenerative diseases and other genetic disorders. The study entitled “RNA Controls PolyQ Protein Phase Transitions” was published in Molecular Cell by researchers from Dartmouth College, New Hampshire, and Princeton…
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